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Empagliflozin synthesis includes C‑glycosidic bond formation, low‑temperature control and stereoselective reduction. Temperature, mixing and residence time govern selectivity and product quality. Continuous-flow microchannel reactors improve heat/mass transfer by microscale effects and allow accurate residence time tuning, offering process intensification for these steps.

This dapagliflozin synthesis case adopts microchannel continuous flow microreactor for stereoselective reduction. It completes the reaction within minutes and obtains crude product purity above 90%. Superior heat-mass transfer cuts side reactions and scale-up risks vs traditional batch processes. Our team provides EPC, process optimization and skid-mounted microreactor services for pharmaceutical API manufacturing.

Baleine Phase 3 FPSO has kicked off hull construction for Côte d’Ivoire’s largest offshore oil & gas discovery. This new-build floating facility will lift field output significantly. Tight space onboard demands compact heat transfer equipment; PCHE offers high efficiency and robustness to meet harsh offshore thermal management requirements.

Jointly developed by Tsinghua University & Shenzhen Tsinghua Research Institute, the modular microchannel continuous flow process revolutionizes Pigment Red 57 manufacturing:

✅ Diazotization finished within ~2 minutes

✅ Liquid holdup reduced from tonne scale to millilitres/litres

✅ Diazonium salt yield >99% | Pigment total yield >99% | Product purity ≥98%

✅ Plant footprint cut by over 75%

✅ Minimal waste liquid output, better resource efficiency

The Inner Mongolia explosion accident resulted from incomplete risk management during continuous flow renovation, with hidden dangers in legacy equipment. Effective upgrading relies on full-process assessment and validated engineering design, not mere hardware replacement.

Shenshi Technology’s Printed Circuit Heat Exchanger (PCHE) stands out with full advantages:

🔹 Low-temperature & high-pressure resistant for -162℃ LNG vaporization

🔹 Diffusion welding monolithic construction, leak-free & vibration-resistant for shipboard use

🔹 Microchannel high-efficiency heat transfer, compact lightweight design to optimize engine room layout

🔹 Anti-freeze blockage patented technology for long-term stable vessel operation

Remdesivir is a nucleotide analog prodrug developed by Gilead Sciences, Inc. that inhibits viral replication by interfering with viral RNA synthesis. During the COVID-19 pandemic, demand grew rapidly, and the limitations of traditional batch processes in terms of safety, production efficiency, and scalability gradually became apparent.

Shenshi unveils corrosion-resistant PCHE for offshore energy at KOE 2026.

Shenshi showcases compact PCHE for LNG FGSS at Korea Ocean Expo 2026.

Explore our 300ml SiC microchannel reactor for efficient continuous flow chemistry.

Tubular reactors cut oxidation time 96.7% & boost capacity 500% in pharma.

Discover how advanced tubular reactors optimize continuous flow chemical manufacturing.

Discover the objective pros & cons of copper vs stainless steel heat exchanger tubes. Learn how 316L stainless steel offers a budget-saving HVAC alternative.

Explore the performance, reliability, and cost-saving benefits of 316L stainless steel inner tube heat exchangers for efficient HVAC & refrigeration systems.