Microchemical & Industrial Processes

This dapagliflozin synthesis case adopts microchannel continuous flow microreactor for stereoselective reduction. It completes the reaction within minutes and obtains crude product purity above 90%. Superior heat-mass transfer cuts side reactions and scale-up risks vs traditional batch processes. Our team provides EPC, process optimization and skid-mounted microreactor services for pharmaceutical API manufacturing.

Jointly developed by Tsinghua University & Shenzhen Tsinghua Research Institute, the modular microchannel continuous flow process revolutionizes Pigment Red 57 manufacturing:

✅ Diazotization finished within ~2 minutes

✅ Liquid holdup reduced from tonne scale to millilitres/litres

✅ Diazonium salt yield >99% | Pigment total yield >99% | Product purity ≥98%

✅ Plant footprint cut by over 75%

✅ Minimal waste liquid output, better resource efficiency

The Inner Mongolia explosion accident resulted from incomplete risk management during continuous flow renovation, with hidden dangers in legacy equipment. Effective upgrading relies on full-process assessment and validated engineering design, not mere hardware replacement.

Remdesivir is a nucleotide analog prodrug developed by Gilead Sciences, Inc. that inhibits viral replication by interfering with viral RNA synthesis. During the COVID-19 pandemic, demand grew rapidly, and the limitations of traditional batch processes in terms of safety, production efficiency, and scalability gradually became apparent.

Explore our 300ml SiC microchannel reactor for efficient continuous flow chemistry.

Tubular reactors cut oxidation time 96.7% & boost capacity 500% in pharma.

Discover how advanced tubular reactors optimize continuous flow chemical manufacturing.

SHENSHI's AFSS Ammonia Heat Exchanger delivers cryogenic marine-grade NH₃ handling with 30% space savings, 20% energy reduction, and Lloyd's Register certification.

Continuous flow Pinnick oxidation enables safe, high-yield synthesis in 3 minutes

Shenshi launches the compact onboard carbon capture system using microchannel technology. Up to 90% smaller, motion-proof, 90%+ CO₂ capture rate. Solves space and sloshing issues of traditional amine towers, achieves 2–3 year payback under EU ETS, ideal retrofit solution for existing fleet to meet IMO 2030/2050 targets.

Microchannel reactors enable efficient, safe chemical synthesis. Shenshi Tech's innovation serves for sustainable processes. Discover more!

Discover efficient plate fin heat exchangers from Shenshi, ideal for aerospace and green energy.